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1

Structure and Molecular Dynamics Simulation of Archaeal Prefoldin: The Molecular Mechanism for Binding and Recognition of Nonnative Substrate Proteins

Akashi Ohtaki, Hiroshi Kida, Yusuke Miyata, Naoki Ide, Akihiro Yonezawa, Takatoshi Arakawa, Ryo Iizuka, Keiichi Noguchi, Akiko Kita, Masafumi Odaka, Kunio Miki, Masafumi Yohda

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2008

2

Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding

Mihoko Takenoya, Akashi Ohtaki, Keiichi Noguchi, Kiwamu Endo, Yasuyuki Sasaki, Kanju Ohsawa, Shunsuke Yajima, Masafumi Yohda

Journal:

Journal of Structural Biology

Année:

2010

Langue:

english

Fichier:

PDF, 728 KB

english, 2010

3

Structure and function of archaeal prefoldin, a co-chaperone of group II chaperonin

Journal:

Frontiers in Bioscience

Année:

2010

Langue:

english

Fichier:

PDF, 510 KB

english, 2010

4

Structure and characterization of amidase from Rhodococcus sp. N-771: Insight into the molecular mechanism of substrate recognition

Akashi Ohtaki, Kensuke Murata, Yuichi Sato, Keiichi Noguchi, Hideyuki Miyatake, Naoshi Dohmae, Kazuhiro Yamada, Masafumi Yohda, Masfumi Odaka

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2010

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2010

5

Structure of a complex of Thermoactinomyces vulgaris R-47 α-amylase 2 with maltohexaose demonstrates the important role of aromatic residues at the reducing end of the substrate binding cleft

Akashi Ohtaki, Masahiro Mizuno, Hiromi Yoshida, Takashi Tonozuka, Yoshiyuki Sakano, Shigehiro Kamitori

Journal:

Carbohydrate Research

Année:

2006

Langue:

english

Fichier:

PDF, 433 KB

english, 2006

6

Recurrent takotsubo cardiomyopathy with variant forms of left ventricular dysfunction

Masaki Izumo, Yoshihiro J. Akashi, Kengo Suzuki, Kazuto Omiya, Fumihiko Miyake, Eiji Ohtaki

Journal:

Journal of Cardiology Cases

Année:

2010

Langue:

english

Fichier:

PDF, 717 KB

english, 2010

7

Complex formation of CdSe/ZnS/TOPO nanocrystal vs. molecular chaperone in aqueous solution by hydrophobic interaction

Hiromi Horiuchi, Noriya Iwami, Fumi Tachibana, Akashi Ohtaki, Ryo Iizuka, Tamotsu Zako, Masaru Oda, Masafumi Yohda, Toshiro Tani

Journal:

Journal of Luminescence

Année:

2007

Langue:

english

Fichier:

PDF, 470 KB

english, 2007

8

Single molecule FRET detection in CdSe-QD donor and Cy5-labeled molecular chaperone acceptor complex by imaging microscopy

Toshiro Tani, Masaru Oda, Hiroshi Sakai, Daisuke Araki, Yoshinori Itoh, Akashi Ohtaki, Masafumi Yohda

Journal:

Journal of Luminescence

Année:

2011

Langue:

english

Fichier:

PDF, 809 KB

english, 2011

9

Role of Phe286 in the recognition mechanism of cyclomaltooligosaccharides (cyclodextrins) by Thermoactinomyces vulgaris R-47 α-amylase 2 (TVAII). X-ray structures of the mutant TVAIIs, F286A and F286Y, and kinetic analyses of the Phe286-replaced mutant TVAIIs

Akashi Ohtaki, Shin Kondo, Yoichiro Shimura, Takashi Tonozuka, Yoshiyuki Sakano, Shigehiro Kamitori

Journal:

Carbohydrate Research

Année:

2001

Langue:

english

Fichier:

PDF, 122 KB

english, 2001

10

Mutual conversion of substrate specificities of Thermoactinomyces vulgaris R-47 α-amylases TVAI and TVAII by site-directed mutagenesis

Akashi Ohtaki, Akihiro Iguchi, Masahiro Mizuno, Takashi Tonozuka, Yoshiyuki Sakano, Shigehiro Kamitori

Journal:

Carbohydrate Research

Année:

2003

Langue:

english

Fichier:

PDF, 375 KB

english, 2003

11

Structure of aspartate racemase complexed with a dual substrate analogue, citric acid, and implications for the reaction mechanism

Akashi Ohtaki, Yohsuke Nakano, Ryo Iizuka, Takatoshi Arakawa, Kazuhiro Yamada, Masafumi Odaka, Masafumi Yohda

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2008

Langue:

english

Fichier:

PDF, 425 KB

english, 2008

12

Energy transfer in hybrid CdSe quantum dots vs. labelled molecular chaperone systems by imaging microscopy

Toshiro Tani, Hiromi Horiuchi, Masaru Oda, Eiji Usukura, Hiroshi Sakai, Akashi Ohtaki, Masafumi Yohda

Journal:

physica status solidi (c)

Année:

2009

Langue:

english

Fichier:

PDF, 239 KB

english, 2009

13

Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase

Yasuaki Yamanaka, Koichi Hashimoto, Akashi Ohtaki, Keiichi Noguchi, Masafumi Yohda, Masafumi Odaka

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 584 KB

english, 2010

14

Acute myocardial infarction in a young adult patient with simultaneous total occlusion of double coronary arteries

Motoki Miyauchi, Masaki Izumo, Yoshihiro J. Akashi, Kengo Suzuki, Shonosuke Ryu, Nobuyuki Hashimoto, Fumihiko Miyake, Sachihiko Nobuoka, Eiji Ohtaki

Journal:

Journal of Echocardiography

Année:

2010

Langue:

english

Fichier:

PDF, 337 KB

english, 2010

15

Global longitudinal strain by two-dimensional speckle tracking imaging predicts exercise capacity in patients with chronic heart failure

Seisyou Kou, Kengo Suzuki, Yoshihiro J. Akashi, Kei Mizukoshi, Manabu Takai, Masaki Izumo, Takashi Shimozato, Akio Hayashi, Eiji Ohtaki, Naohiko Osada, Kazuto Omiya, Sachihiko Nobuoka, Fumihiko Miyake

Journal:

Journal of Echocardiography

Année:

2011

Langue:

english

Fichier:

PDF, 765 KB

english, 2011

16

Structure and direct electrochemistry of cytochrome P450 from the thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain 7

Yusuke Oku, Akashi Ohtaki, Shigehiro Kamitori, Nobuhumi Nakamura, Masafumi Yohda, Hiroyuki Ohno, Yutaka Kawarabayasi

Journal:

Journal of Inorganic Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 816 KB

english, 2004

17

The crystal structure of Thermoactinomyces vulgaris R-47 α-amylase II (TVA II) complexed with transglycosylated product

Masahiro Mizuno, Takashi Tonozuka, Akiko Uechi, Akashi Ohtaki, Kazuhiro Ichikawa, Shigehiro Kamitori, Atsushi Nishikawa, Yoshiyuki Sakano

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 582 KB

english, 2004

18

X-ray Structures of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor Provide Insights into Stereoselective Reductions of Carbonyl Compounds

Shigehiro Kamitori, Akihiro Iguchi, Akashi Ohtaki, Mitsugu Yamada, Keiko Kita

Journal:

Journal of Molecular Biology

Année:

2005

Langue:

english

Fichier:

PDF, 493 KB

english, 2005

19

Functional Characterization of Recombinant Prefoldin Complexes from a Hyperthermophilic Archaeon, Thermococcus sp. Strain KS-1

Ryo Iizuka, Yuri Sugano, Naoki Ide, Akashi Ohtaki, Takao Yoshida, Shinsuke Fujiwara, Tadayuki Imanaka, Masafumi Yohda

Journal:

Journal of Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 942 KB

english, 2008

20

Thermodynamic Characterization of the Interaction between Prefoldin and Group II Chaperonin

Muhamad Sahlan, Tamotsu Zako, Phan The Tai, Akashi Ohtaki, Keiichi Noguchi, Mizuo Maeda, Hideyuki Miyatake, Naoshi Dohmae, Masafumi Yohda

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2010

21

Structural characterization of the organic solvent-stable cholesterol oxidase from Chromobacterium sp. DS-1

Martin Sagermann, Akashi Ohtaki, Keith Newton, Noriyuki Doukyu

Journal:

Journal of Structural Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2010

22

Crystal Structures and Structural Comparison of Thermoactinomyces vulgaris R-47 α-Amylase 1 (TVAI) at 1.6 Å Resolution and α-Amylase 2 (TVAII) at 2.3 Å Resolution

Shigehiro Kamitori, Akemi Abe, Akashi Ohtaki, Akira Kaji, Takashi Tonozuka, Yoshiyuki Sakano

Journal:

Journal of Molecular Biology

Année:

2002

Langue:

english

Fichier:

PDF, 952 KB

english, 2002

23

Crystal Structures of Aspergillus oryzae Aspartic Proteinase and its Complex with an Inhibitor Pepstatin at 1.9 Å Resolution

Shigehiro Kamitori, Akashi Ohtaki, Hironori Ino, Michio Takeuchi

Journal:

Journal of Molecular Biology

Année:

2003

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2003

24

Monooxygenation by a thermophilic cytochrome P450 via direct electron donation from NADH

Matsumura, Hirotoshi, Matsuda, Keisuke, Nakamura, Nobuhumi, Ohtaki, Akashi, Yoshida, Hiromi, Kamitori, Shigehiro, Yohda, Masafumi, Ohno, Hiroyuki

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.16 MB

english, 2011

25

Structure-Based Peptide Mimicry of Tumor-Associated Antigens

Ohtaki, Akashi, Kieber-Emmons, Thomas, Murali, Ramachandran

Journal:

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

Année:

2013

Langue:

english

Fichier:

PDF, 137 KB

english, 2013

26

Two arginine residues in the substrate pocket predominantly control the substrate selectivity of thiocyanate hydrolase

Yamanaka, Yasuaki, Arakawa, Takatoshi, Watanabe, Toshinori, Namima, Satoshi, Sato, Masa, Hori, Shota, Ohtaki, Akashi, Noguchi, Keiichi, Katayama, Yoko, Yohda, Masafumi, Odaka, Masafumi

Journal:

Journal of Bioscience and Bioengineering

Année:

2013

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2013

27

Relationship between left ventricular ejection fraction and mitral annular displacement derived by speckle tracking echocardiography in patients with different heart diseases

Suzuki, Kengo, Akashi, Yoshihiro J., Mizukoshi, Kei, Kou, Seisyou, Takai, Manabu, Izumo, Masaki, Hayashi, Akio, Ohtaki, Eiji, Nobuoka, Sachihiko, Miyake, Fumihiko

Journal:

Journal of Cardiology

Année:

2012

Langue:

english

Fichier:

PDF, 748 KB

english, 2012

28

Mutations in K-Ras linked to levels of osteoprotegerin and sensitivity to TRAIL-induced cell death in pancreatic ductal adenocarcinoma cells

Kanzaki, Hirotaka, Ohtaki, Akashi, Merchant, Faisal K., Greene, Mark I., Murali, Ramachandran

Journal:

Experimental and Molecular Pathology

Année:

2013

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2013

29

31P NMR Studies on Sulfur/Oxygen-Bridged Incomplete Cubane-Type Molybdenum Cluster Compounds. X-ray Structures of [Mo3OS3(DTP)4(CH3CN)] and [Mo3OS3(OAc)(DTP)2(Py)2(OC2H5)]

Yao, Yuangen, Akashi, Haruo, Sakane, Genta, Shibahara, Takashi, Ohtaki, Hitoshi

Journal:

Inorganic Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 797 KB

english, 1995

30

Modulation of Redox Potential and Alteration in Reactivity via the Peroxide Shunt Pathway by Mutation of Cytochrome P450 around the Proximal Heme Ligand †

Matsumura, Hirotoshi, Wakatabi, Masahiro, Omi, Sayaka, Ohtaki, Akashi, Nakamura, Nobuhumi, Yohda, Masafumi, Ohno, Hiroyuki

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 297 KB

english, 2008

31

Carbonyl Sulfide Hydrolase from Thiobacillus thioparus Strain THI115 Is One of the β-Carbonic Anhydrase Family Enzymes

Ogawa, Takahiro, Noguchi, Keiichi, Saito, Masahiko, Nagahata, Yoshiko, Kato, Hiromi, Ohtaki, Akashi, Nakayama, Hiroshi, Dohmae, Naoshi, Matsushita, Yasuhiko, Odaka, Masafumi, Yohda, Masafumi, Nyunoya,

Journal:

Journal of the American Chemical Society

Année:

2013

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2013

32

Value of anatomical aortic valve area using real-time three-dimensional transoesophageal echocardiography in patients with aortic stenosis: a comparison between tricuspid and bicuspid aortic valves

Machida, T., Izumo, M., Suzuki, K., Yoneyama, K., Kamijima, R., Mizukoshi, K., Takai, M., Kobayashi, Y., Harada, T., Miyake, F., Ohtaki, E., Nobuoka, S., Matsumoto, N., Akashi, Y. J.

Journal:

European Heart Journal - Cardiovascular Imaging

Année:

2015

Langue:

english

Fichier:

PDF, 687 KB

english, 2015

33

Changes in mitral regurgitation and left ventricular geometry during exercise affect exercise capacity in patients with systolic heart failure

Izumo, M., Suzuki, K., Moonen, M., Kou, S., Shimozato, T., Hayashi, A., Akashi, Y. J., Osada, N., Omiya, K., Miyake, F., Ohtaki, E., Lancellotti, P.

Journal:

European Journal of Echocardiography

Année:

2011

Langue:

english

Fichier:

PDF, 286 KB

english, 2011

34

Three-dimensional echocardiographic assessments of exercise-induced changes in left ventricular shape and dyssynchrony in patients with dynamic functional mitral regurgitation

Izumo, M., Lancellotti, P., Suzuki, K., Kou, S., Shimozato, T., Hayashi, A., Akashi, Y. J., Osada, N., Omiya, K., Nobuoka, S., Ohtaki, E., Miyake, F.

Journal:

European Journal of Echocardiography

Année:

2009

Langue:

english

Fichier:

PDF, 280 KB

english, 2009

35

Improvement of enantioselectivity of the B-type halohydrin hydrogen-halide-lyase from Corynebacterium sp. N-1074

Watanabe, Fumiaki, Yu, Fujio, Ohtaki, Akashi, Yamanaka, Yasuaki, Noguchi, Keiichi, Odaka, Masafumi, Yohda, Masafumi

Journal:

Journal of Bioscience and Bioengineering

Année:

2016

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2016

36

Crystal structures of halohydrin hydrogen-halide-lyases from Corynebacterium sp. N-1074

Watanabe, Fumiaki, Yu, Fujio, Ohtaki, Akashi, Yamanaka, Yasuaki, Noguchi, Keiichi, Yohda, Masafumi, Odaka, Masafumi

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2015

Langue:

english

Fichier:

PDF, 906 KB

english, 2015

37

2P096 Molecular characterization of prefoldins from a hyperthermophilic archaeon, Thermococcus sp. strain KS-1(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

Sugano, Yuri, Iizuka, Ryo, Ohtaki, Akashi, Ide, Naoki, Yoshida, Takao, Fujiwara, Shinsuke, Imanaka, Tadayuki, Yohda, Masafumi

Journal:

Seibutsu Butsuri

Année:

2006

Langue:

english

Fichier:

PDF, 163 KB

english, 2006

38

Hyperventilation and cold-pressor stress echocardiography combined with automated functional imaging non-invasively detected vasospastic angina

Suzuki, K., Akashi, Y. J., Mizukoshi, K., Kou, S., Takai, M., Izumo, M., Shimozato, T., Hayashi, A., Ohtaki, E., Nobuoka, S., Miyake, F.

Journal:

Année:

2010

Fichier:

PDF, 878 KB

2010